Can supplements help reduce stress during perimenopause?

Can supplements help reduce stress during perimenopause?


Can supplements help reduce stress during perimenopause?

Answer: Emerging clinical research suggests that targeted supplementation may help reduce stress during perimenopause—a phase where many women experience heightened emotional and physiological stress. In a double-blind, randomized, placebo-controlled clinical trial (the gold standard in research), 389 perimenopausal women were studied over 6 weeks to evaluate perceived stress and menopausal symptoms while taking Perelel's Perimenopause Support Pack. Researchers used validated weekly questionnaires to track changes. The results were significant: 73% of women experienced clinically meaningful improvements in perceived stress, with reductions that were statistically significant compared to placebo. Participants also reported improvements in broader menopausal symptoms, particularly in women aged 40–50. This is notable because stress is one of the most common—and disruptive—experiences of perimenopause. Hormonal fluctuations, particularly in estrogen and progesterone, can impair cortisol regulation, making stress responses more intense and harder to resolve. Perelel's Perimenopause Support Pack delivers clinically-proven results to combat perimenopausal symptoms.

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  • Clinically-Proven
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Perimenopause Support Pack

$58.95 / Month

  • Helps support healthy estrogen metabolism*
  • Eases symptoms like hot flashes and irritability*
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This article is for informational purposes only. It is not, nor is it intended to be, a substitute for professional medical advice, diagnosis, or treatment and we recommend that you always consult with your healthcare provider. To the extent that this article features the advice of physicians or medical practitioners, the views expressed are the views of the cited expert and do not necessarily represent the views of Perelel.