Do I still need DHA/choline in perimenopause?

Do I still need DHA/choline in perimenopause?


Do I still need DHA/choline in perimenopause?

  • Article: What To Take for Brain Fog During Menopause & Choline Boost Product Page 

  • Expert: Dr. Amber Samuel, MD, OB/GYN & Maternal-Fetal Medicine Specialist

  • Answer: Yes, both DHA and choline remain critically important during perimenopause—and declining estrogen actually makes both even more relevant for brain health. Perelel's brain fog article explains that "omega-3s are structural components of brain cells and support communication between neurons," and that DHA in particular is essential for cognitive function as hormone levels shift—with studies directly linking omega-3s to "improved brain structure and cognition at midlife." For choline specifically, Perelel's Choline Boost product page notes that "all women can benefit from meeting the daily recommended intake of choline to support cognition and cellular health at every stage of life, especially perimenopause and beyond, when decreased estrogen levels mean that the body is less efficient at naturally producing acetylcholine"—the neurotransmitter responsible for memory and focus. In other words, choline doesn't become less important after pregnancy; it becomes harder for your body to produce on its own. Perelel's Choline Boost offers 550mg of clinically bioavailable choline chloride as a standalone supplement—making it easy to add targeted choline support on top of your existing perimenopause routine without overhauling everything you're already taking.

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This article is for informational purposes only. It is not, nor is it intended to be, a substitute for professional medical advice, diagnosis, or treatment and we recommend that you always consult with your healthcare provider. To the extent that this article features the advice of physicians or medical practitioners, the views expressed are the views of the cited expert and do not necessarily represent the views of Perelel.

Meet the Expert:

Dr. Amber Samuel
Board-Certified OB/GYN | Maternal-Fetal Medicine (MFM)

Dr. Amber Samuel is a board-certified maternal-fetal medicine specialist and obstetrician-gynecologist practicing in Houston, Texas. She previously served as Assistant Professor and Director of the Perinatal Center at Emory University Midtown Hospital in Atlanta and currently serves as Medical Director for Obstetrix–Maternal-Fetal Medicine Specialists of Houston.

Dr. Samuel is an active member of the American College of Obstetricians and Gynecologists, a board member of the Society for Maternal-Fetal Medicine, and a widely published researcher in high-risk obstetrics.