Essential 2nd Trimester Prenatal Vitamin Bundle

Folic acid is a synthetic form of folate, or vitamin B9—a nutrient that plays an essential role in DNA synthesis and early neural tube development. While "folic acid" is often used interchangeably, this synthetic form requires more processing by the body to become active folate—and up to 60% of women have a genetic variation that makes it difficult to effectively utilize folic acid.

Since folate is crucial for early pregnancy, it was important to our medical panel that we include the most bioavailable form of folate possible—in the form of L-5 methylfolate, as substantiated by medical research and their own clinical insights. "Folic acid is less expensive, [which] leads to the terms folate and folic acid being interchangeable," says Dr. Amber Samuel, a maternal-fetal medicine doctor and Perelel panelist. "We know that while everyone has to convert folic acid for it to be useful, [it's] an added step, decreasing bioavailability. And some women cannot due to MTHFR mutations."

According to one study published in Clinical Pharmacokinetics: "Bioavailability studies have provided strong evidence that L-5-methyl-THF is at least as effective in improving folate status, as measured by blood concentrations of folate and by functional indicators of folate status, such as homocysteine."
A direct quote from this study is the below as well for reference:
"Studies comparing L-5-methyl-THF and folic acid have found that the two compounds have comparable physiological activity, bioavailability and absorption at equimolar doses. Bioavailability studies have provided strong evidence that L-5-methyl-THF is at least as effective as folic acid in improving folate status, as measured by blood concentrations of folate and by functional indicators of folate status, such as plasma homocysteine. Intake of L-5-methyl-THF may have advantages over intake of folic acid."

Yes, we complete third-party testing on all of our products to confirm purity and potency. All of our vitamins are made in FDA Registered and Inspected Facilities, which meet FDA 21 CFR 111 guidelines and are also cGMP Certified. All raw materials for our vitamins are tested directly prior to production to ensure their purity and quality. COAs are performed on every batch of manufactured vitamins to ensure final product integrity and quality, which includes testing for heavy metals, microbes, allergens and contaminates. We then complete third-party testing for heavy metals, microbes and potency to confirm our products are safe under USP standards.  In addition, our pre and postnatal formulas have earned us certification from the Clean Label Project, a leading nonprofit that sets one of the industry's highest standards for consumer transparency. We’re proud to have earned Clean Label Project’s highest honor, the Purity Award!

If you're interested in learning more, check out our blog post here on heavy metals.

While the timing of when you start your vitamins with us doesn't always exactly align with your trimester, rest assured all of our packs will keep your needs covered during any overlap weeks! Feel free to finish out your current pack before switching to your new one.

2nd Trimester Pack contains magnesium, which is shown to support relaxation. That said, we also recommend checking out our Sleep Support, a pregnancy-safe drink powder with a doctor-backed Magnesium Blend to support a restful sleep.

We chose to source omegas from fish because they are heavily research backed. To help reduce heavy metals in the final oil, we are also sourcing from smaller wild caught fish like anchovies and sardines.

An enteric coated HPMC (hydroxypropyl methylcellulose) capsule is a capsule meant to survive the gastric juices of the stomach in order to make it to the intestines, where it will dissolve. Our team has found that using this specialized capsule helps with nausea and stomach upset.

Remember to always take your vitamins on a full stomach and with a full glass of water.

Each monthly Pack contains 30 daily sachets (with 5 pills each) to cover all your needs during the 2nd trimester.

Perelel is the first and only prenatal vitamin brand co-founded by an OB/GYN. For each of our formulations, our medical co-Founder, Dr. Bayati, partners with a panel of leading doctors and women's health experts—drawing on both the latest scientific research and their own clinical insights to help select high-quality ingredients in their most bioavailable forms, in clinically-tested doses.

Our bodies and baby's needs change so much during pregnancy. Unlike most one-size-fits-all prenatal vitamins, our Trimester Packs were specifically designed to change with you—delivering targeted nutrition and symptoms relief when you need it most.

Our products run on a monthly subscription to make sure you never run out of your vitamins. Your subscription will automatically update alongside your due date so you receive the right pack for your trimester and into postpartum.

We account for shipping time and will automatically move you into the next trimester pack as you start to approach it. You will receive an email 5 days prior to any shipment just in case you need to make any adjustments (such as changing packs or moving back a shipment).

We follow the American College of Obstetricians and Gynecologists™ (ACOG) defined trimesters:

• 1st Trimester: Week 0 through Week 13
• 2nd Trimester: Week 14 through Week 27
• 3rd Trimester: Week 28 through Week 40+

Always feel free to contact us at [email protected] if you have any specific questions or want to make any changes.

This product is FSA/HSA eligible. Learn more here.

Synbiotic Greens Powder, Cellular Hydration Powder, Triple-Support Protein, Sleep Support, Daily Probiotic and Daily Iron Ease are all safe for pregnancy and can be safely paired with your Prenatal Multivitamin Pack.

We included the PhytoServ™ Fruit Blend because it provides the antioxidant equivalent of a full serving of fruit. Synbiotic Greens Powder also has 7% of your daily value for fiber.

Yes - our Synbiotic Greens Powder* is safe for pregnancy and safe for breastfeeding.

Yes, we complete third-party testing on all of our products to confirm purity and potency. All of our vitamins are made in FDA Registered and Inspected Facilities, which meet FDA 21 CFR 111 guidelines and are also cGMP Certified. All raw materials for our vitamins are tested directly prior to production to ensure their purity and quality. COAs are performed on every batch of manufactured vitamins to ensure final product integrity and quality, which includes testing for heavy metals, microbes, allergens and contaminates. We then complete third-party testing for heavy metals, microbes and potency to confirm our products are safe under USP standards.  In addition, our pre and postnatal formulas have earned us certification from the Clean Label Project, a leading nonprofit that sets one of the industry's highest standards for consumer transparency. We’re proud to have earned Clean Label Project’s highest honor, the Purity Award!

If you're interested in learning more, check out our blog post here on heavy metals.

You can enjoy Synbiotic Greens with water, juice, or blended into a smoothie! Our dietitians developed some great recipes here.

Our Synbiotic Greens Powder has a subtly sweet açaí flavor with notes of berry and bright lemon.

There is no need to stop taking your current Probiotic with the Greens Powder unless a personal preference for it to replace your probiotic as it does have different strains as well as a prebiotic. Combining the two products actually diversifies the probiotics strains you’re taking even more. The probiotics in the Daily Probiotic are from the Lactobacillus and Bifidobacterium genus, while the probiotic in the Greens & Synbiotic Powder is from the Bacillus genus. The live strain probiotics in Daily Probiotic will also benefit from the prebiotic inulin in the greens.

We specifically created our Synbiotic Greens Powder to not have any added vitamins or minerals above its ingredients so it will layer safely with your existing vitamin routine.

All of our products are manufactured in the USA at high-quality partners that follow FDA's current Good Manufacturing Practices (cGMPs) to ensure quality and safety. Our ingredients are sourced throughout the world to ensure we have the cleanest and most bioavailable formats of each vitamin or mineral.

Our Medical Co-Founder, Dr. Bayati, a practicing OB/GYN, formulated our products utilizing her many years of clinical experience and the latest research. She partnered with our Perelel Panel of doctors & experts to make sure a woman's needs are covered, and there was no overdosing and underdosing at any time.

At Perelel, we believe that credentials matter. That’s why we’ve pulled together an exclusive team of world-class doctors and leading experts to inform all that we do. What does that mean for you? Our Perelel Panel of doctors and practitioners formulates all Perelel products, informs product development, and fuels our content–giving you access to the best.

While the FDA does not approve dietary supplements, our vitamins are made in an FDA Registered and Inspected Facility, which meets FDA 21 CFR 11 guidelines and is also cGMP Certified. We manufacture our products in accordance with the FDA’s current Good Manufacturing Practices (cGMPs) to ensure quality and safety. All raw materials for our vitamins are tested directly prior to production to ensure their purity and quality. Certificates of analysis (COA) are performed on every batch of manufactured vitamins to ensure final product integrity and quality, which includes testing for heavy metals, microbes, allergens and contaminates. Additionally, all our products are free of harmful additives, GMO ingredients, and most allergens!

Yes! In a double blind, randomized, placebo controlled clinical trial, 83% of women experienced clinically meaningful improvement in GI issues (including belly pain, gas and bloating, diarrhea and constipation) after 12 weeks.†

The amount of hyaluronic acid in your skin is one of the primary measures of skin hydration. Various conditions—from your environment to aging—can deplete hyaluronic acid levels. Both internal and external hydration matter—but ultimately, we we eat and consume is what makes up the building blocks of our skin!

We use bovine collagen peptides in our product which are rich in hydroxyproline, glycine and proline. (And therefore, this product is not vegetarian or vegan.) Cellular Hydration delivers type I and III collagen. Type I collagen is the most abundant protein in your body and comprises approximately 80% of your skin's structure.

Yes, we complete third-party testing on all of our products to confirm purity and potency. All of our vitamins are made in FDA Registered and Inspected Facilities, which meet FDA 21 CFR 111 guidelines and are also cGMP Certified. All raw materials for our vitamins are tested directly prior to production to ensure their purity and quality. COAs are performed on every batch of manufactured vitamins to ensure final product integrity and quality, which includes testing for heavy metals, microbes, allergens and contaminates. We then complete third-party testing for heavy metals, microbes and potency to confirm our products are safe under USP standards.  In addition, our pre and postnatal formulas have earned us certification from the Clean Label Project, a leading nonprofit that sets one of the industry's highest standards for consumer transparency. We’re proud to have earned Clean Label Project’s highest honor, the Purity Award!

If you're interested in learning more, check out our blog post here on heavy metals.

We use 6 electrolytes in our hydration product, including sodium, potassium, chloride, magnesium, calcium, phosphate that all play a role in keeping cellular water in and repleting minerals that have been lost.

Yes! Cellular Hydration contains a daily supply of collagen for ultimate skin health.

Cellular Hydration is breastfeeding-safe and a source of electrolytes, which can be especially beneficial for postpartum replenishment. It also contains sunflower lecithin, which is traditionally used to support lactation health.*

Yes! And is a source of electrolytes, which is especially beneficial while pregnant or postpartum.

A refreshing, naturally-flavored mango lemonade drink mix. It tastes great mixed into water or blended into a smoothie.